Reviewed by Dr. Goh Ming Chun, MD (Universiti Putra Malaysia), MAC, AAAM. Trained at the Plastic & Reconstructive Surgery Department, Penang General Hospital. Specialises in scar management.

What Is Rejuran?
Rejuran is a polynucleotide (PN) injectable derived from salmon DNA. It works by stimulating fibroblasts where the cells responsible for producing collagen and elastin to repair and regenerate skin from within. It does not add volume. It rebuilds skin quality.Read our complete honest guide to Rejuran skin booster Malaysia before deciding which type suits you.The 4 Rejuran Types - Side by Side
| Type | Formulation | Best For | Texture |
|---|---|---|---|
| Healer | Standard PN | Overall skin quality, dullness, fine lines | Liquid |
| I | Thin, low-viscosity PN | Delicate areas: under-eyes, lips | Ultra-fine liquid |
| HB | PN + HA blend | Hydration + repair combined | Semi-viscous |
| S | High-concentration PN | Acne scars, deeper texture issues | Gel-like |
Which Type Do You Need?
Rejuran Healer – For Most Skin Concerns
The original formulation. Best for patients who want overall improvement on dull skin, feels rough, fine lines are appearing. This is what most first-timers receive.
Rejuran I – For Sensitive or Thin-Skin Areas
Ultra-thin consistency designed for delicate zones: under-eye hollows, lip lines, crepey neck skin. Too thin for general face use, results are subtle but precise where it counts.
Rejuran HB – For Dehydrated Skin That Also Needs Repair
Combines PN with hyaluronic acid. Good for patients whose skin is both dry and damaged, common in Malaysia’s air-conditioned heavy lifestyle. You get the hydration of a skin booster plus the cellular repair of standard Rejuran.
Rejuran S – For Acne Scars and Texture Damage
Higher PN concentration in a thicker gel. Designed specifically for depressed acne scars and deep texture irregularities. Requires proper scar assessment first, not every scar type responds to PN alone.
For patients dealing with acne scarring, see our guide to acne scar types and treatments in Malaysia to understand which treatment combination works best.
Can You Combine Types?
Yes. Dr. Goh often uses Rejuran I around the eye area while using Healer or HB across the rest of the face in the same session. The right combination depends on your skin assessment, not a one-size approach.
How Many Sessions?
Most patients see meaningful improvement after 2-3 sessions spaced 4 weeks apart. Maintenance every 6 months. Results build gradually, skin looks progressively healthier over 4-8 weeks post-treatment.

Frequently Asked Questions
Is Rejuran the same as filler?
No. Rejuran does not add volume or change facial structure. It rebuilds skin quality at a cellular level — texture, hydration, tone. Fillers reshape. Rejuran repairs.
Does Rejuran hurt?
A topical numbing cream is applied before treatment. Most patients describe mild pressure and brief stinging. Downtime is 24–48 hours of small bumps (papules) that resolve on their own.
Which Rejuran type is best for anti-aging?
Rejuran Healer for general anti-aging. Rejuran HB if your skin is also dehydrated. Rejuran I for fine lines around the eyes and mouth. See the full breakdown of each Rejuran type.
How is Rejuran different from Profhilo?
Profhilo is hyaluronic acid — it hydrates and stimulates collagen through a different mechanism. Rejuran is polynucleotide — it repairs at a cellular level. Many patients benefit from both.
Is Rejuran suitable for sensitive skin?
Yes — Rejuran’s anti-inflammatory properties often make it a good choice for reactive or sensitive skin types.
Who is not a candidate?
Patients who are pregnant, breastfeeding, have active skin infections, or are allergic to fish products (salmon DNA source). Book a consultation to assess your suitability.
